Wales wing Josh Adams has been ruled out of the Six Nations trip to face Scotland in Murrayfield on Saturday.

Cardiff wing Adams, 29, missed the 27-18 loss to Ireland in Cardiff with a hamstring problem and has not recovered in time for this weekend.

Gloucester fly-half Gareth Anscombe has recovered from a head knock suffered against Ireland and is available for selection.

Ospreys hooker Dewi Lake is also in contention for a return after missing the first three Six Nations defeats because of an arm injury.

Wales have lost a record 15 Test matches in a row with interim head coach Matt Sherratt taking over from Warren Gatland before the Ireland defeat.